Dr. Henry Friedman

Biography

Henry Seth Friedman is the James B. Powell, Jr. Distinguished Professor of Pediatric Oncology at Duke Cancer Institute. His research focuses on the biology and therapy of central nervous system malignancies, including high-grade medulloblastoma and gliomas, using a variety of models such as human tumor cell lines and patient tumor specimens. He has led studies that define the chemotherapeutic profiles of these cancers and their mechanisms of resistance to traditional alkylating agents. He has also been central in clinical trials translating these laboratory findings into treatments for both adults and children, demonstrating significant activity with several chemotherapy regimens. Dr. Friedman has received numerous grants to support his research and has published extensively in the field, contributing to the understanding of malignant brain tumors and new therapeutic strategies. He continues to lead future studies that aim to innovate cancer treatments through exploration of signal pathway inhibitors and novel drug delivery methods.

Research Interests

Experience