Dr. Hey Kyoung Lee

Biography

Hey-Kyoung Lee is a Professor in the Solomon H. Snyder Department of Neuroscience at Johns Hopkins University. His research focuses on the cellular and molecular mechanisms of synaptic plasticity that are crucial for memory formation and how these processes are influenced by daily experiences. The lab studies the changes that occur at synapses during learning and memory, including long-term potentiation (LTP) and long-term depression (LTD). Additionally, they explore global homeostatic synaptic plasticity, particularly in response to sensory loss, such as vision loss, and its impact on excitatory synaptic transmission in the primary visual cortex. Lee collaborates with Dr. Philip Wong at Johns Hopkins School of Medicine and Dr. Hyang-Sook Hoe at Georgetown University to analyze mouse models of Alzheimer's disease, focusing on alterations in synaptic plasticity mechanisms associated with the condition. Lee aims to elucidate the fundamental mechanisms that allow the brain to adapt based on experience and to understand the pathological changes that occur in neurodegenerative conditions.

Research Interests