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Hjalmar Brismar is a Professor at KTH Royal Institute of Technology in the Division of Biophysics. His research group, Understanding Cellular Dynamics, investigates the fundamental physical principles that govern biological processes at the cellular level. A key focus of his work involves the Na,K-ATPase, a vital ion pump that is crucial for intracellular homeostasis. He has pioneered the field of Na,K-ATPase signaling, demonstrating how the endogenous ligand ouabain triggers intracellular calcium oscillations, which play critical roles in cellular stress responses and protective mechanisms against apoptosis in pathological conditions. His current research projects delve into the allosteric regulation of the Na,K-ATPase catalytic subunit and its interaction with other cellular components, employing advanced imaging techniques that he has helped innovate. He is a leader in super-resolution microscopy and coordinates national infrastructure for microscopy at the Science Life Laboratory, collaborating closely with the Karolinska Institutet.
Department of Women’s Children’s Health, Karolinska Institutet • Sweden
Department of Applied Physics, KTH • Sweden
Science Life Laboratory • Sweden
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