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Hong Ling is a Professor in the Department of Biochemistry at Western University. He received his Ph.D. from the University of Alberta and subsequently completed a postdoctoral fellowship at the National Institutes of Health. His research laboratory focuses on identifying the molecular mechanisms of DNA damage management in cells. His ongoing projects include the regulation of translesion DNA synthesis, which allows DNA replication to bypass damaged sites, a critical mechanism for cell survival. The studies aim to reveal the structure-function relationship of Y-family polymerases and their interactions with TLS regulatory proteins, which is significant in understanding cancer development and drug resistance caused by specific DNA lesions. He employs X-ray crystallography, molecular biology, and protein chemistry in his research endeavors. He has received numerous awards for his contributions to research, including the Canada’s Premier Young Researcher Award and the Early Researcher Award from the Ontario Ministry of Research Innovation.
Western University • London, Ontario, Canada
Teaching and conducting research in the Department of Biochemistry, focusing on DNA damage and repair mechanisms.
Streams include Archaeology and Bioarchaeology, and Sociocultural Anthropology.