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Howard Lipshitz is a Professor in the Department of Molecular Genetics at the University of Toronto. His research focuses on functional genomics and proteomics, particularly involving CRISPR-Cas9 genome engineering and Drosophila models. He investigates post-transcriptional regulation during the maternal-to-zygotic transition in early embryos and neural lineages in the developing brain using a range of techniques, including genetics, genomics, transcriptomics, proteomics, and computational biology. Additionally, Lipshitz examines the mechanisms underlying rare human diseases linked to mutations in RNA-binding proteins (RBPs) and has initiated research into the role of RBPs in autism spectrum disorder (ASD). His work often employs phage-displayed synthetic antibodies to recognize RBPs implicated in these diseases. With a commitment to unraveling the complexities of gene regulation and expression, he contributes significantly to the fields of neurodegeneration, stem cell biology, and the development of novel disease models.
Department of Sociology