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Professor Howard Young has been a member of the Biochemistry department for 22 years, engaging in innovative research that explores heart cells and the underlying mechanisms of calcium metabolism, which plays a crucial role in muscle contraction and relaxation. His work focuses on the dysfunctions associated with heart failure and hereditary heart diseases, aiming to elucidate the genetic defects that affect calcium metabolism. Young's research has led to the identification of new mutations linked to heart failure, and he has worked on understanding the role of proteins such as phospholamban, sarcolipin, and DWORF in calcium regulation. His approach combines biochemical techniques with structural biology methodologies, including X-ray crystallography and cryogenic electron microscopy. The research carries vital implications for developing therapeutic strategies for heart disease, fostering a detailed comprehension of the disease-related mechanisms. Young's contributions to molecular cardiac research have been acknowledged through numerous publications in prestigious journals, making a significant impact on the field.
University of Alberta • Edmonton, AB
Engaged in teaching and research focusing on molecular mechanisms of heart disease.
Department: Mechanical Engineering and Engineering Management