Dr. Hue Chan

Biography

Hue Sun Chan was born and raised in Hong Kong. He completed his undergraduate degree in physics and pursued graduate study in theoretical particle physics at the University of California, Berkeley, specializing in the regularization of quantum field theories. After receiving his PhD in 1987, he joined Ken Dill's research group at the University of California, San Francisco, where he was a postdoctoral fellow and adjunct faculty, shifting his research interest to protein biophysics. Chan has made seminal contributions to the theoretical studies of protein folding since the late 1980s, including discovering secondary-structure-like local order that enhances global conformational compactness, developing the HP model, and characterizing the role of kinetic traps in the folding energy landscape. In 1998, he took his present appointment in Toronto, where he has focused on the physical origins of folding cooperativity and broadened his research interests to include thermodynamics, solvent-mediated interactions, and protein interactions involving intrinsically disordered proteins. He has published over 155 research papers, receiving more than 20,000 citations, and serves on the editorial board of Proteins: Structure, Function & Bioinformatics. His research aims to elucidate the energetics underlying protein folding and interactions through theoretical and computational investigations.

Research Interests

Experience

Awards