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Hui Shi is a Postdoctoral Fellow in the Department of Pharmacology at the University of Washington. His research focuses on the molecular basis of diseases with a particular emphasis on the ERAD pathway and its components. Utilizing structural biology techniques such as cryo-electron microscopy and x-ray crystallography, he investigates the role of RING finger protein 139 (RNF139) in regulating cellular homeostasis. His work aims to uncover the molecular details of how RNF139 operates within the ERAD pathway, providing significant insights into mechanisms that could be beneficial for further studies and the development of therapeutic strategies for various cancers, particularly renal cell carcinoma.
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