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Hui Sun is a Professor in the Department of Physiology at UCLA Health Jonsson Comprehensive Cancer Center. His research focuses on the mechanistic study of new therapeutic targets to treat cancer. His lab has discovered a long-sought receptor that interacts with vitamin A, which is expressed at over 100 times higher levels in cancer tissues compared to normal tissues. Sun's team is investigating how cancer-inhibiting chemicals affect receptor-mediated influx of retinoids, further inhibiting cell growth. Additionally, his research includes studying the secreted factor PEDF, which has demonstrated broad therapeutic value in treating various diseases due to its antiangiogenic, antitumorigenic, and antimetastatic activities. Numerous animal models have shown PEDF's capability to inhibit a wide range of cancer types, including prostate and pancreatic cancers, melanoma, and glioma, among others. Sun's continued investigation focuses on the cellular mechanisms of PEDF receptors to develop specific and potent therapeutics.
Department of Economics admits primarily for the PhD program.