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Ian Tobias is an Assistant Professor at the Ontario Veterinary College, University of Guelph, specializing in comparative genomics with a focus on gene regulation in neural development. His research aims to integrate genome editing and stem cell technologies to create models of mammalian development, investigating cis-regulatory elements that influence cell differentiation and patterning in neural tissues. Further, he studies the regulation of chromatin remodeling, transcription factors, and epigenetic modifications that play critical roles in cell fate reprogramming and cancer. His lab seeks to elucidate the biological mechanisms that control brain development, particularly how variation in genetic makeup influences neurological traits and disease susceptibility across species. Tobias' research combines computational and empirical methods to explore the evolutionary changes in DNA sequence that affect gene regulation, contributing to our understanding of inherited neurological disorders. He is devoted to using functional genomics and genome-editing techniques to address fundamental questions in neurodevelopment and the genetic causes of movement disorders in both humans and companion animals. By leveraging knowledge from the human genome, he aims to tailor prevention and treatment strategies to specific patient subgroups based on their unique patho-mechanistic features.
Ontario Veterinary College, University of Guelph • Guelph, ON, Canada
Engaged in research and teaching in the field of comparative genomics and neural development.
Department of Clinical Studies. Offers MSc by thesis (2 years) and MSc by coursework (1 year).