Dr. Ingeborg Schmidt Krey

Biography

Ingeborg Schmidt-Krey is an Associate Professor in the School of Chemistry and Biochemistry at the Georgia Institute of Technology. She earned her B.S. in Biochemistry from Mississippi State University in 1991 and obtained her Ph.D. in Biophysics with a focus on Structural Biology from the Karolinska Institute in 1999. Her research primarily investigates eukaryotic membrane proteins, which account for 60% of drug targets and are critical in biomedical research. In her lab, she employs electron crystallography as a main tool for studying the structure and function of these proteins. The approach involves testing conditions for growing two-dimensional crystals and reconstituting detergent-solubilized membrane proteins into phospholipid bilayers. Once crystallization is achieved, she utilizes electron microscopy and cryo-EM to gather high-resolution data. Schmidt-Krey is also developing screening methods aimed at enhancing the 2D crystallization process and understanding the mechanisms behind it. Her research interests extend into the application of these methods in the analysis of inflammation and cancer.

Research Interests