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Isaac Fianu is an Assistant Professor of Biochemistry at Caltech, focusing on gene regulation and genome stability. He obtained his B.Sc. from the University of Ghana in 2012 and completed his M.Sc./PhD at the University of Göttingen, Germany, in 2020. Fianu then pursued postdoctoral research at the Max Planck Institute for Multidisciplinary Science in Germany from 2020 to 2024. His research employs biochemistry and structural biology techniques, particularly cryo-electron microscopy, to investigate critical processes that control gene expression and respond to cellular conditions. Fianu's work emphasizes the importance of RNA Polymerase II and its regulation by the Integrator complex, which is linked to several diseases and developmental disorders. He is interested in the coordination of DNA transcription, replication, and repair to avoid genome instability, providing insights that may lead to new therapeutic approaches. Fianu is currently seeking new team members, including postdoctoral and graduate student candidates, to join his research efforts.
California Institute of Technology • Pasadena, CA
Teaching and conducting research in the field of biochemistry with a focus on gene regulation and genome stability.
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