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Issam Ben-Sahra is a Thomas D. Spies Professor in the Department of Biochemistry and Molecular Genetics at Northwestern University Feinberg School of Medicine. His research focuses on genetic metabolism and the metabolic changes that occur in response to cellular signaling pathways, particularly in cancer cells. His lab defines how normal physiological processes such as cell growth and immune responses are altered in cancer through changes in nucleotide synthesis and metabolic activity. Ben-Sahra's studies utilize advanced techniques, including mass spectrometry, to analyze metabolic flux and alterations in metabolite concentrations in both malignant and non-malignant cells. His work aims to elucidate the molecular mechanisms by which cancer cells enhance their growth and proliferation, potentially leading to new therapeutic strategies for eradicating cancer. He holds an MS and PhD from the University of Sophia-Antipolis in France and completed his postdoctoral training at Harvard School of Public Health. Ben-Sahra has participated in numerous studies published in prestigious journals, exploring various aspects of metabolism in cancer and other diseases.
Harvard School of Public Health • Boston, MA
Conducted research in genetic metabolism.
Administered by The Graduate School; focuses on Biomechanics, Imaging, Biomaterials, and Regenerative Medicine.