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Ivan Luptak is an Associate Professor in the Chobanian & Avedisian School of Medicine at Boston University. He specializes in cardiovascular medicine, with a focus on myocardial energy metabolism. His research employs multinuclear NMR spectroscopy to assess contractile function and energy metabolite dynamics in the heart. Luptak's studies investigate the modulation of energy substrate utilization as a potential therapeutic approach for cardiac hypertrophy and heart failure, revealing insights into how glucose and fatty acid metabolism shifts can protect heart function. His work also highlights the role of AMP kinase in metabolic remodeling associated with familial cardiac syndromes. Additionally, Luptak explores how mitochondrial metabolism and reactive oxygen species influence cardiac function during ischemic events. His research interests extend to understanding the implications of obesity and diabetes on myocardial energetics, showcasing the potential benefits of new treatments. Luptak's contributions to the field include investigating the effects of SGLT2 inhibition on mitochondrial function and developing energetically favorable therapies that aim to improve outcomes for patients with heart failure.
Boston University • Boston, MA
Specializes in cardiovascular medicine and myocardial energy metabolism.
Department of Law offers JD, LLM, and Master's in Study of Tax Law.