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Jack Donald Keene is a distinguished professor with a focus on molecular genetics and microbiology at Duke University. His laboratory has a long-standing interest in the structure and function of viral and mammalian genomes. Over the years, his research contributions have included discerning genomic sequences related to rabies, Ebola, and other viruses, leading to significant findings in the role of RNA-binding proteins in autoimmune reactivity. Keene's current research centers around the functional roles of human RRM-ELAV/Hu proteins, which are known to bind a subset of cellular mRNAs influencing various biological processes such as growth regulation and neuronal plasticity. His innovative 'ribonomics' approach has allowed the identification of mRNA clusters regulated post-transcriptionally, enhancing the understanding of gene expression organization within genomes. Through his numerous grants awarded by the National Institutes of Health, he continues to advance research in fields including bioinformatics and cancer biology.
Department of Biomedical Engineering (MS program)