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Dr. Jacob S. Brenner is an Assistant Professor in the Department of Medicine at the University of Pennsylvania, specializing in Pulmonary, Allergy, and Critical Care. He is board certified and fellowship-trained in critical care medicine. Dr. Brenner is the director of the Brenner Bioengineering Lab, where he focuses on the intersection of nanotechnology and medicine, particularly in developing novel gene therapy solutions. His research interests include DNA-loaded lipid nanoparticles (DNA-LNPs) for treating various chronic and acute conditions, with a strong emphasis on improving therapeutic strategies for diseases such as cystic fibrosis, hemophilia, and cancer. Notable areas of study include understanding the toxicological profiles of these therapies and utilizing complexity science to explore disease dynamics. Dr. Brenner also teaches courses on nanomedicine and medical entrepreneurship at the Penn.
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