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Jacqueline Lees is the Virginia D.K. Ludwig Professor at the Massachusetts Institute of Technology (MIT) in the Department of Biology. Her research focuses on the development of mouse and zebrafish models to identify the molecular pathways that lead to tumor formation. By using a combination of molecular and cellular analyses, as well as genetic screens in mutant mouse models, she aims to establish the mechanisms of action in normal tumor cells. Her work contributes significantly to the field of cancer research and the understanding of tumorigenicity, revealing critical insights into the biology of cancer and potential therapeutic targets.