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James Chen received A.B. and Ph.D. degrees in Chemistry and Chemical Biology from Harvard University, and completed postdoctoral studies at the Department of Molecular Biology and Genetics at Johns Hopkins University. He joined the Stanford faculty in 2003, and his research interests span organic chemistry, chemical biology, developmental biology, and cancer biology. The Chen lab investigates the molecular mechanisms underlying tissue formation and tumorigenesis, guided by chemical principles that enable the development of chemical technologies. Notable achievements include the development of small-molecule inhibitors of Hedgehog signaling, which is vital for various aspects of embryonic development and contributes to human cancer. His group discovered specific inhibitors of cytoplasmic dyneins, which are microtubule motors regulating signaling in the primary cilium. Chen's lab applies tools such as zebrafish embryos to elucidate transcriptional programs regulating the development of key tissues and has devised novel methods for time-resolved lanthanide microscopy to enable ultrasensitive imaging of whole organisms.
Stanford University • Stanford, California
Professor in the Chemical Systems Biology.
The Computer Science department emphasizes research potential. GRE General is currently optional but recommended for some tracks.