Generate a tailored SOP for Dr. James Dear. Improve your application with a focused, well-structured draft.
James Dear is a Reader at the University of Edinburgh, specializing in the improvement of diagnosis and management of acute medical emergencies through the understanding of the clinical utility of circulating microRNAs. With over ten years of research experience, his work has demonstrated that microRNAs can serve as significant disease biomarkers and mechanisms of cellular signaling, which are amenable to therapeutic intervention. His focus on microRNA biomarkers related to drug toxicity has substantial implications for clinical patient care and the development of commercial drugs. In particular, he has researched paracetamol (acetaminophen) overdose, a leading cause of acute liver failure in the Western world, resulting annually in over 100,000 emergency presentations and over 50,000 hospital admissions in the UK alone. The biomarkers developed by his team promise to transform clinical practices by allowing for the early exclusion of liver injury and improving the identification of drug-induced liver injury, which is crucial for the pharmaceutical industry. His research group has established a portfolio of pre-clinical models exploring microRNAs in toxicology and cell-to-cell signaling, including the development of a new zebrafish model for liver toxicity studies.
Department of Marketing