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James Dignam's primary research focuses on the design, conduct, and analysis of cancer clinical trials, including early development (phase II) and definitive evaluation (phase III) trials. He serves as Executive Director of the Statistics Data Management Center at NRG Oncology, which is a National Cancer Institute sponsored multi-center clinical trials group involving 500 recruitment sites across North America and managing 100 active clinical trials. Dr. Dignam's methodological interests encompass trial monitoring, early stopping rules, competing risks, hazard function estimation, and prognostic modeling. He has led investigations into the impact of sociodemographic factors, such as race/ethnicity and body mass index (BMI) on cancer prognosis and treatment response. He teaches courses in introductory biostatistics, clinical trials, survival analysis, and regression modeling methods.
Department of Philosophy