Dr. James Eberwine

Biography

James H. Eberwine is the Elmer Holmes Bobst Professor of Pharmacology at the University of Pennsylvania's Perelman School of Medicine. He is a member of several prestigious institutions, including the Institute of Neurological Sciences, the Abramson Cancer Center, the Center for Bioinformatics, the Institute for Medicine Engineering, the Genomics Institute, and the Center for Cell Engineering. As Co-Director of the PENN Program in Single Cell Biology and the Penn Center for Subcellular Genomics, his research focuses on the molecular basis of neuronal adaptation, particularly adaptive processes, and its implications for understanding the functioning of neurons. His significant expertise in molecular biology allows for the examination of gene expression in single cells under various experimental conditions. Eberwine has developed innovative techniques for studying individual cells, focusing on mRNA localization and translation, and contributing to the understanding of how these processes affect neuronal function. He aims to generate molecular bioprocess fingerprints for various cell types and disease states, ultimately seeking to predictably alter cellular responses to challenges through biological interventions.

Research Interests