Dr. James Garnett

Biography

James Garnett is a Reader in Microbial Structural Biology at King’s College London, where he leads a research group focused on understanding the molecular mechanisms that promote bacterial diseases. His major research interests lie in the study of biofilm formation, a key virulence trait that allows bacteria to establish and persist in infections within hosts and the environment. He received his PhD from the Astbury Centre for Structural Molecular Biology at the University of Leeds, where he explored transcriptional regulation of L-arginine metabolism in bacteria. Subsequently, at Imperial College London, he investigated novel virulence mechanisms in various microbes, including bacteria and fungi. In 2015, he established a research group at Queen Mary University of London to study the type II secretion mechanisms of Legionella pneumophila. Garnett has held positions at King’s College since 2019, where he became a Reader in 2022. His laboratory's activities also span antimicrobial resistance and the development of new anti-biofilm therapeutics to combat infectious diseases, particularly in contexts such as dental caries, periodontitis, and chronic inflammatory diseases. Additionally, he collaborates with multiple departments within King’s to foster interdisciplinary research connecting microbial health and disease.

Research Interests

Experience