Dr. James Klinger

Biography

James R. Klinger is a Professor of Medicine and the Medical Director of the Pulmonary Hypertension Center at Rhode Island Hospital. He completed his fellowship in pulmonary critical care medicine at Brown University after completing his residency in internal medicine at the Medical College of Pennsylvania. Dr. Klinger is an NIH-funded basic science investigator whose research interests include natriuretic peptides, cGMP signaling pathways, pulmonary hypertension, right ventricular hypertrophy, and pulmonary endothelial barrier function. His recent investigations have explored the role of bone marrow progenitor cells, extracellular vesicles, and transcription factors in the pathogenesis of pulmonary hypertension. Additionally, his clinical research focuses on the use of investigational agents to treat adult patients with pulmonary arterial hypertension. He serves as the chair of the program committee for the Pulmonary Circulation Assembly of the American Thoracic Society and is the co-chair of the American College of Chest Physicians Guidelines Committee for the Treatment of Pulmonary Hypertension. Dr. Klinger has edited two textbooks on Pulmonary Arterial Hypertension and is involved in several steering committees for clinical trials and educational programs. He is also a member of the Scientific Liaison Committee of the Pulmonary Hypertension Association and the Pathobiology Task Force for the 2018 World Symposium on Pulmonary Hypertension. Dr. Klinger is on the faculty of the American Thoracic Society and serves as an Associate Editor for the journal "Lung."

Research Interests