Dr. James Provenzale

Biography

James Michael Provenzale is a Professor in the Department of Radiology at Duke University. His research focuses on diffusion tensor imaging (DTI), a magnetic resonance technique that measures the rate and direction of microscopic water motion to examine white matter pathways in the brain. His recent work has centered on histological correlation of DTI metrics and the variability of these metrics across different scanners and time points, with efforts aimed at understanding the causes of this variability. Dr. Provenzale has mentored third-year medical students at the Duke University School of Medicine in research related to DTI and perfusion imaging. His research is particularly tailored for individuals with advanced computer skills and an interest in biomedical electrical engineering. He collaborates closely with both basic science and clinical departments and engages students in the research process, culminating in co-authorship on manuscripts produced from their projects. His interests extend to the applications of nanotechnology in cancer treatment, particularly for central nervous system and non-CNS tumors, and he has been involved in developing non-invasive and minimally invasive monitoring devices. Dr. Provenzale has received multiple NIH grants supporting his work and has held previous appointments as Chief of Neuroradiology and Associate Professor in Radiology.

Research Interests

Experience