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James Self completed his higher specialist training in Paediatric Ophthalmology and holds a PhD in Ophthalmic Molecular Genetics. His overarching research aim is to improve the lives of children with eye disorders. His research interests cover a range of conditions affecting children's vision, including nystagmus, albinism, genetic eye disorders, amblyopia, and paediatric cataract. Dr. Self leads a team that combines expertise in genetics, bioinformatics, wet-lab modelling, eye-tracking, and clinical trials to enhance the diagnosis and treatment of these disorders. He is actively engaged in public engagement activities, delivering lectures and open sessions for over a decade. Dr. Self also advises multiple vision charities and has roles in various professional committees, including the Royal College of Ophthalmologists. He has supervised several PhD students and is involved in mentoring, aiming to ensure that research translates into real clinical impact for children with vision disorders.