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James M. Wilson, MD, PhD, is an Emeritus Professor in the Department of Medicine at the University of Pennsylvania, specializing in Translational Medicine and Human Genetics. His extensive research career spans over four decades, during which he has been a pioneer in the field of gene therapy. Dr. Wilson's laboratory focuses on the development of gene transfer vectors for the treatment of inherited and acquired diseases. He has been instrumental in discovering novel viral vectors, particularly adeno-associated viruses (AAV), which have become the industry standard for gene therapy applications. His work has led to advancements in therapeutic genome editing and gene delivery mechanisms, particularly in targeting the liver and central nervous system. He has also contributed to several successful gene therapy clinical programs for rare genetic diseases. In addition to his innovative research, Dr. Wilson guides graduate students and postdoctoral researchers in cutting-edge projects related to gene editing and vector engineering, fostering the next generation of biomedical scientists.
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