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Jamie Spangler is an Assistant Professor in the Whiting School of Engineering at Johns Hopkins University, where she also serves as the director of the Spangler Lab at the Johns Hopkins School of Medicine. Her research is focused on expanding the repertoire of protein therapeutics by redesigning naturally occurring proteins and engineering new molecules to overcome deficiencies of existing drugs. She integrates cutting-edge tools from structural biophysics, biomolecular engineering, and translational immunology, with an aim to develop innovative platforms for discovery and design of proteins that can recruit novel mechanisms for disease therapy. Spangler's interests particularly include engineering antibody-based molecules to reshape immune cell behavior for targeted treatment of cancer, infectious diseases, and autoimmune disorders. Her overarching goal is to establish new insights into protein behavior and its potential manipulation for medically relevant applications. She earned her Bachelor of Science in Biomedical Engineering from Johns Hopkins University in 2006 and her Ph.D. in Biological Engineering from MIT in 2011, completing her postdoctoral training at Stanford University School of Medicine before joining the faculty at Johns Hopkins in 2017.
Johns Hopkins University • Baltimore, MD
Teaching and conducting research in biomedical engineering and chemical biomolecular engineering.
Department of Biomedical Engineering (PhD). Focus areas: Biomedical Data Science, Computational Medicine, Genomics, Imaging, Immunoengineering, Neuroengineering.