Dr. Jane Rylett

Biography

Dr. Jane Rylett is a professor in the Department of Physiology and Pharmacology at Western University. She obtained her Ph.D. from the University of Western Ontario and conducts research at the Robarts Research Institute. Her research laboratory focuses on cellular and molecular neurobiology, with a particular emphasis on presynaptic function of cholinergic neurons. Dr. Rylett’s work addresses fundamental questions related to the regulation of cholinergic neurons and neurochemical communication, particularly in the context of aging and diseases such as Alzheimer’s. With a keen interest in the physiological processes governed by cholinergic neurons, her studies contribute to our understanding of learning, memory, and the neurodegenerative processes that lead to cognitive decline. Recent investigations in her lab have identified key regulatory mechanisms involved in cholinergic neuronal protein function, advancing the field’s understanding of neurotransmitter transporters and their role in neuronal health. She is actively involved in collaborative studies related to mild cognitive impairment and the early phases of Alzheimer’s disease, utilizing advanced imaging techniques to improve diagnostic accuracy and track disease progression.

Research Interests