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Janis K. Burkhardt is a Professor in the Department of Pathology and Laboratory Medicine at the Perelman School of Medicine, University of Pennsylvania. With a distinguished academic career, Dr. Burkhardt focuses her research on the regulatory mechanisms of cytoskeletal dynamics and their implications in immune responses, particularly involving T cells and dendritic cells. Her laboratory investigates how the cytoskeleton affects immune cell signaling, antigen presentation, and overall immune system efficacy. Using various methodologies, she examines actin regulatory proteins and their roles in immunodeficiency and autoimmune diseases. Her research has significant implications for cancer immunotherapy and vaccine development, aiming to enhance the functionality of immune cells in response to tumors and infections.
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