Dr. Jason Bazil

Biography

Jason Bazil is an Assistant Professor in the College of Natural Science at Michigan State University, specializing in the study of ischemic heart disease, a leading cause of mortality worldwide. His research focuses on understanding the mechanisms behind myocardial infarction and the lethal injury it precipitates, particularly regarding mitochondrial involvement. According to the American Heart Association, a significant portion of American myocardial infarctions results in death within minutes. These alarming statistics demonstrate the need for a deeper understanding of the conditions that lead to myocardial injury. Dr. Bazil's lab employs integrative strategies that combine computational modeling and experimental physiology to characterize the phenomena surrounding these injuries. The lab is developing therapeutic strategies aimed at characterizing the mechanisms of mitochondrial dysfunction that contribute to heart disease. They are also examining lethal reperfusion injury through monitoring mitochondrial responses to calcium overload and oxidative stress, and are developing methods for large-scale data analysis to improve the interpretability of big data in their research.

Research Interests

Experience