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Dr. Jason Northey is an Assistant Professor in the Department of Biochemistry at the University of Alberta. He completed his Ph.D. at McGill University and pursued postdoctoral research at the University of California, San Francisco. His research focuses on the biomechanical and biochemical cues that direct cell fate and development, which are critical for maintaining tissue homeostasis. Dr. Northey's work investigates the effects of elevated extracellular matrix stiffness on integrin mechanosignaling, particularly in the context of metastatic breast cancer. His group is exploring how genetically engineered mouse models, organoid cultures, and hydrogels can be used to study the mechanical forces influencing mammary gland development and breast cancer progression, with an emphasis on steroid hormone responses and epigenetic regulation. Through this research, Dr. Northey aims to understand how the tumor microenvironment can affect cell behavior and inspire new strategies for breast cancer prevention and treatment.
University of Alberta • Edmonton, AB
Teaching and research in the Department of Biochemistry, focusing on the mechanisms of breast cancer.
Department: Mechanical Engineering and Engineering Management