Dr. Jason Tanny

Biography

Jason Tanny is an Associate Professor in the Department of Pharmacology and Therapeutics at McGill University. He received his PhD in Cell Developmental Biology from Harvard Medical School in 2003. Following his doctoral studies, he completed a postdoctoral fellowship at Rockefeller University from 2003 to 2007, and subsequently at Université de Montréal from 2007 to 2008. His research focuses on gene regulation and covalent histone modifications and their impact on mechanisms of human disease. He investigates fundamental questions regarding histone modifications, specifically their role in establishing active genes and their functions in gene expression. Tanny employs a variety of approaches, including classical chemical genetics, genomics, biochemistry, and proteomics, utilizing yeast and mammalian model systems to elucidate the molecular functions of histone modifications. His most recent work has unveiled a novel link between the ubiquitylation of histone H2B and the conserved transcription elongation factor P-TEFb, with the ultimate aim of targeting histone modifications and relevant modifying enzymes to develop new therapeutic avenues for various diseases.

Research Interests

Experience