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Jasreen Kular completed her PhD studies at the University of Western Australia in 2012, focusing on discovering novel regulators of bone homeostasis that can be translated into therapeutic targets for osteoporosis, arthritis, and Paget’s disease of bone. In 2013, she commenced a postdoctoral position at the Centre for Cancer Biology in Adelaide under Professor Michael Samuel, where her work identified 14-3-3ζ as a novel negative regulator of mechanoreciprocity that limits epidermal regeneration, potentially halving the healing time for chronic wounds. In 2022, she returned to Perth to join the Kids Research Institute, where she utilized her skills in cell biology and cell signaling pathways to study Group A Streptococcus (GAS) research in Dr. Tim Barnett's laboratory. Currently, Dr. Kular is back at the University of Western Australia in the laboratory of Associate Professor Nathan Pavlos, leading the 'Lyso-bone' theme in Bone Biology Diseases. Her research aims to understand the molecular mechanisms regulating secretory lysosomes and their role in modulating osteoclastic bone resorption, with the overall goal of identifying novel therapeutic targets for lysosomal storage disorders and debilitating musculoskeletal diseases like osteoporosis, osteoarthritis, and Paget’s disease.
University of Western Australia • Perth
Leading research on the 'Lyso-bone' theme in Bone Biology Diseases, focusing on novel therapeutic targets.
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