Generate a tailored SOP for Dr. Jay Rajagopal. Improve your application with a focused, well-structured draft.
Jay Rajagopal's research program focuses on understanding airway regeneration and lung stem cell biology. He explores fundamental topics in stem cell biology, including size regulation, maintenance, metaplasia, epithelial organization, cell fate determination, axis formation, and cellular plasticity using a mammalian airway model system. His specific interest lies in how abnormal activation of developmental pathways contributes to human lung diseases, particularly the process of metaplasia related to cancer. Rajagopal is actively pursuing methods to generate actual human models of disease, such as growing human airway stem cells ex vivo, creating humanized mouse models of disease, and utilizing human airway explants, as well as patient-specific airway epithelium induced-pluripotent stem cells. His recent work includes collaboration with experts in novel imaging modalities, epigenetics, and computational biology.
Harvard Stem Cell Institute • Boston, MA
Leading research in airway regeneration and stem cell biology, focusing on human disease models.
Administered by the Harvard Kenneth C. Griffin Graduate School of Arts and Sciences (GSAS).