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Jean-Philippe Gratton has been leading the Endothelial Cell Biology unit at the Clinical Research Institute of Montreal since 2002. He serves as the head of the Department of Pharmacology at the University of Montreal and has held the Canada Research Chair in Endothelial Cell Signaling and Angiogenesis since 2013. His research focuses on the mechanisms controlling the proliferation, survival, and differentiation of endothelial cells, which line blood vessels and are crucial for blood flow regulation and the development of new vessels. By employing modern pharmacological techniques and molecular biology, his team investigates how intracellular movements of the vascular endothelial growth factor (VEGF) receptor affect its signaling and the release of nitric oxide (NO) from endothelial cells. His work has vital implications in cardiovascular diseases and tumor angiogenesis, seeking to uncover new signaling components that impact endothelial function and propose novel therapeutic targets for vascular pathologies.
Most programs require French B2 level; specific departments may require C1 or C2.