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Jenna L. Galloway is an Associate Professor in the Department of Orthopedic Surgery at Harvard University. The research laboratory led by Galloway focuses on enhancing the molecular understanding of the formation and regeneration of tendons and ligaments. Injuries to these tissues often result in a slow and imperfect regenerative response, where the restoration of original biomechanical properties may lead to scarring and limited mobility. The laboratory employs a multidisciplinary approach, integrating genetic and chemical screening with model systems such as zebrafish and stem cells, to identify essential regulators of tendon and ligament biology. A central goal of Galloway's research is to uncover the cues that direct progenitor cells to mature into tendons and ligaments. This involves studying progenitor cell populations during embryogenesis and elucidating pathways that regulate cell fate decisions while expanding tendon and ligament populations. Galloway's work aims to identify critical factors that coordinate the attachments between muscle, tendon, and bone, utilizing live-imaging and high-throughput screening techniques to discover the molecules and cellular behaviors involved in these processes. Overall, the long-term vision of her laboratory is to translate discoveries in regenerative biology into solutions for healing and repairing tendon and ligament injuries.
Administered by the Harvard Kenneth C. Griffin Graduate School of Arts and Sciences (GSAS).