Dr. Jennifer Phillips Cremins

Professor

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Biography

Jennifer E. Phillips-Cremins is the James S. McDonnell Professor and a BJC Investigator in the Departments of Genetics and Neuroscience at Washington University in St. Louis. Her research focuses on the intricate relationships between chromatin structure and function, emphasizing the mechanisms that dictate genome organization and gene expression. She investigates how alterations in chromatin dynamics can lead to neurological diseases, including Alzheimer’s disease and other neurodegenerative disorders. Phillips-Cremins has significantly contributed to our understanding of 3D genome folding and the regulatory roles of insulators and architectural proteins in chromatin interactions. Her work combines molecular biology, genetics, and neuroscience techniques to elucidate the etiology of various neurobiological conditions, aiming to identify potential therapeutic targets for treatment. She has authored numerous publications in high-impact journals, including Nature Genetics and Cell, and is recognized as a leading figure in the field of neurobiology and chromatin research.

Research Interests