Dr. Jenny Wang

Biography

Jenny Wang is a Conjoint Senior Lecturer at the University of New South Wales (UNSW) in the School of Clinical Medicine and leads the Cancer Stem Cell Laboratory at the Children's Cancer Institute. She returned to Sydney in 2011 after completing her postdoctoral research at Harvard Medical School, focusing on leukemia stem cell biology. Dr. Wang's lab concentrates on developing novel therapies targeting malignant stem cells that are resistant to chemotherapy, which are believed to be the root of treatment failure and cancer relapse. Her research highlights the self-renewal capabilities of stem cells and how genetic and epigenetic abnormalities enable malignant stem cells to evade treatment and regenerate new tumors. The laboratory aims to identify critical drug targets for eradicating malignant stem cells and develop effective therapies for difficult-to-treat leukemias, including acute myeloid leukemia (AML). Dr. Wang's significant studies have elucidated key self-renewal pathways and promising therapeutic opportunities that specifically target leukemia stem cells. Additionally, she explores the epigenetic regulation of leukemia stem cells and their roles in cancer progression, and is developing RNA-based therapeutics, particularly focusing on non-coding RNAs in leukemia. Her work has the potential to lead to the development of novel therapies that selectively kill cancer stem cells, addressing the root causes of disease progression and tumor resistance to chemotherapy.

Research Interests

Experience