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Jesse Goyette received his PhD in the School of Medical Sciences at UNSW Sydney in 2009, awarded the Nuffield Medical Fellowship to continue post-doctoral training at Oxford University. From 2011 to 2016, he collaborated with Professor Anton van der Merwe to develop a generic ligand system investigating immune receptor function, resulting in a patented algorithm for analyzing tethered signaling reactions using surface plasmon resonance. In 2016, Jesse returned to Australia, briefly working as a senior post-doctoral researcher at the EMBL Australia Node of Single Molecule Sciences. He currently leads the Lymphocyte Signaling Group at the Single Molecule Sciences, employing an interdisciplinary approach that incorporates biochemical and biophysical advanced imaging methods to study molecular signaling pathways in T cells. His research focuses on understanding how T cells transmit signals to initiate immune responses, investigate the modifications in the signaling machinery, and decipher the function of individual components in the T cell receptor complex. By imaging T cells with modified receptors using super-resolution microscopy, Jesse aims to identify critical elements essential for a robust T cell response, influencing the properties of T cell signals. He probes the molecular mechanisms that integrate multiple cell surface receptor signals into functional outcomes, utilizing a combination of biochemical techniques and advanced microscopy to guide future experimental work.
The University of New South Wales • Sydney, Australia
Leads the Lymphocyte Signaling Group and conducts research on molecular signaling pathways in T cells.
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