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Jessica Teeling's research focuses on the interplay between the immune system and neurodegenerative diseases, particularly the development of novel immunotherapies aimed at treating conditions driven by misfolded proteins such as amyloid and synuclein. Her team investigates the role of live bacterial infections and the oral gut microbiome in the systemic inflammation that contributes to the onset and progression of neurodegenerative diseases, utilizing clinical samples as well as post-mortem tissue. The research includes a range of in vitro and in vivo biological assays designed to measure inflammation and neural function. Teeling leads several active projects concerning blood-brain barrier permeability and its implications in Alzheimer's disease, and has collaborated with various esteemed researchers and institutions throughout her career. She also coordinates undergraduate modules in immunology and biosciences at the University of Southampton, where she integrates teaching about innovative drug discovery as part of the curriculum.
University of Southampton • Southampton, UK
Conducts research on neurodegenerative diseases and teaches immunology.
Validation of cathepsin B as a therapeutic target.