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Jiali Yu is a Research Investigator in the Department of Surgery at the University of Michigan. She received her PhD from the University of Science and Technology of China in 2017, which was followed by her role as a Research Fellow at the University of Michigan Medical School starting in 2018. Since then, she has focused her research on dissecting the immune regulatory mechanisms within the tumor microenvironment (TME), specifically identifying pathways aimed at improving the efficacy of cancer immunotherapy. Her work has identified immunosuppressive macrophages within the liver metastatic TME that mediate therapeutic resistance to immunotherapy and radiotherapy. She has published significant findings in high-impact journals, including Nature Medicine and Cell Reports, regarding the strategic targeting of lipid kinase PIKfyve and the metabolism-driven heterogeneity of macrophages in the TME. Her recent publications explore critical aspects of tumor immunity and highlight her contributions to the field of cancer research. Jiali Yu joined the faculty at the University of Michigan in 2023 and continues to mentor students and junior researchers in the intricacies of immunotherapy and cancer biology.
University of Michigan • Ann Arbor, MI
Research Investigator in Department of Surgery focusing on immune regulatory mechanisms in tumor microenvironment.
University of Michigan Medical School • Ann Arbor, MI
Conducted research on immune mechanisms related to cancer treatment.
Department of Electrical Engineering and Computer Science