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Jian Hu is a Professor in the Department of Biochemistry at Michigan State University. His research focuses on the structural biology of membrane proteins, particularly metal transporters and their role in biological systems. His lab employs multidisciplinary approaches including X-ray crystallography, cryo-electron microscopy, nuclear magnetic resonance spectroscopy, biochemistry, and biophysics to elucidate the mechanisms of action of these macromolecules at atomic resolution. Major projects include investigating the structural basis of the ZIP family of metal transporters, rational engineering of plant ZIPs to reduce heavy metal contamination, and developing ZIP-specific inhibitors for cancer therapeutics. His contributions to the field have been recognized through various publications detailing the molecular basis of zinc-dependent endocytosis and the catalytic mechanisms of key enzymes.
Yale University • New Haven, CT
Conducted research on structural biology and enzymology.
Department of Psychology