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Collins Lab at MIT focuses on synthetic biology, employing engineering principles to model, design, and build synthetic gene circuits and programmable cells. The lab aims to create novel classes of diagnostics and therapeutics. Researchers utilize deep learning approaches to discover new genetic parts and enhance the synthetic biology design process. The lab is involved in the Antibiotics-AI Project, which harnesses artificial intelligence to rapidly discover novel classes of antibiotics and enhance understanding of their functionality. Through de novo design, the team works on the development of new antibiotics and combination treatments, representing a sophisticated intersection of computer science and biology. Collins Lab operates within the Institute for Medical Engineering and Science, the Synthetic Biology Center, the Computational Systems Biology Initiative, and the Microbiology Graduate Program at MIT, contributing to a multidisciplinary approach in tackling complex challenges in healthcare.