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Jing Huang is a Professor in the Department of Pharmacology at UCLA. His research focuses on longevity and the mechanisms by which dietary restrictions can extend lifespan and mitigate age-related diseases. Huang's work has identified alpha-ketoglutarate (a-KG) as a crucial metabolite that serves as a direct molecular link between nutrient signals and mitochondrial processes, impacting the regulation of mTOR, a major aging regulator. His lab has demonstrated the potential of endogenous molecules like a-KG in increasing longevity, suggesting the existence of internal interventions for aging. Huang is also engaged in method development for technologies that could lead to effective and safe therapies for age-related diseases, including cancer, heart disease, diabetes, and neurodegenerative disorders. His innovative approach, DARTS (Drug Affinity Responsive Target Stability), facilitates the identification of molecular targets for small molecules, a key aspect of developing therapeutic drugs while minimizing adverse effects. Through his research, Huang contributes significantly to the understanding and treatment of aging-related diseases.
Department of Economics admits primarily for the PhD program.