Dr. Jiou Wang

Biography

Jiou Wang is the Walder Distinguished Professor in the Solomon H. Snyder Department of Neuroscience at Johns Hopkins University. His research focuses on the biological basis of protein and RNA homeostasis, particularly in relation to neurodegeneration. He aims to solve problems that have important implications for understanding and treating diseases, particularly neurodegenerative diseases such as Alzheimer's, Parkinson's, and amyotrophic lateral sclerosis (ALS). His research involves discovering key regulators of protein homeostasis, elucidating the mechanisms connecting misfolded proteins to neurodegeneration, and using unbiased genetic screens to understand how cells enhance protein quality control to counteract the effects of misfolded proteins. Furthermore, he investigates the regulation of protein synthesis under stress conditions and its implications in various human diseases. Wang also studies novel pathways of RNA processing and the biology of hexanucleotide repeat expansion in C9orf72 gene, which is a common cause of ALS and frontotemporal dementia (FTD). He is looking for postdoctoral candidates to lead these exciting studies.

Research Interests