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Joanna Hester is an Associate Professor co-leader of the Translational Research Immunology Group (TRIG) at the Nuffield Department of Surgical Sciences, University of Oxford. Her research focuses on understanding the mechanisms of immunological tolerance versus immune activation, specifically in the context of developing therapies for transplant recipients and patients with immune-related diseases. She has a particular interest in the regulatory properties of immune cells, such as regulatory T cells (Treg) and myeloid-derived suppressor cells, and the mechanisms of suppression utilized by these cells. Her research has provided data on the in vivo efficacy of ex vivo expanded human Treg, which has helped inform a current clinical study testing the safety and efficacy of Treg cells in kidney transplant recipients. Joanna collaborates with colleagues at Oxford on projects investigating the effectiveness of cancer immunotherapy and changes in immune response to cancer through both animal models and clinical trials.
Department of Politics and International Relations - Higher Level English requirement.