Dr. Joanne Lemieux

Biography

Joanne Lemieux is a Professor in the Department of Biochemistry at the University of Alberta, having earned her Ph.D. from New York University in 2002 and her M.Sc. from Dalhousie University in 1994. Her research focuses on exploring proteins involved in disease using X-ray crystallography and biophysical techniques to elucidate their structural and functional mechanisms. Dr. Lemieux's major research interest is centered on viral proteases, particularly the main protease of SARS-CoV-2 and related viruses. Her lab develops peptidomimetic inhibitors specifically targeted to inhibit these proteases in vitro and in cellular assays, aiming to create highly potent clinical inhibitors for therapeutic use. Additionally, her work encompasses membrane transporters such as SERCA and Gluts, along with the investigation of small molecule immune checkpoint inhibitors for enhanced cancer therapies. She is recognized for her contributions to drug design and the mechanisms of proteases in relation to various diseases, including insights into treatments for viral infections and cancer.

Research Interests

Experience