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Professor Joel Mackay is a physical biochemist focused on protein structure and function engineering, particularly the molecular mechanisms underlying eukaryotic gene regulation. He obtained his PhD from the University of Cambridge in 1994 and moved to the University of Sydney the following year. Over his illustrious career, Professor Mackay has established a vibrant research laboratory in the School of Life and Environmental Sciences. With over 195 published papers, 87% in the top 10% of journals, his work has garnered approximately 8000 citations, confirming his stature in the field. As the current Chair of Biochemistry and the President of the Australian Society for Biochemistry and Molecular Biology, he leads a group dedicated to understanding protein function at a molecular level. His research emphasizes cutting-edge library display technology to design new proteins and peptides tailored for specific functions. Mackay's lab has proven productivity over 25 years, supported by around $30 million in grants. His major findings include elucidating the roles of zinc fingers in transcription factors and the mechanism of alpha-globin in hemoglobin assembly, contributing significant insights into diseases like beta-thalassemia and sickle cell anemia. He actively collaborates internationally and contributes to undergraduate teaching, supervising honors and PhD students.
University of Sydney • Sydney, Australia
Leading research and teaching efforts in biochemistry and molecular biology.
This entry applies to Faculty of Science PhD programs including Departments such as Life and Environmental Sciences, Physics, Chemistry, and Mathematics and Statistics.