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John Crosby is an Associate Professor at the University of Bristol, holding a B.Sc. from Hull and a Ph.D. from Edinburgh. He specializes in enzymology and polyketide biosynthesis, focusing on the use of a broad range of techniques to study protein expression and purification, enzyme kinetics, and the mass analysis of large biomolecules through electrospray mass spectrometry. His research aims to isolate individual enzymes and establish their structural details and kinetic characteristics to understand the biosynthetic pathways they control fully. Crosby’s work has significant implications for the synthesis of biologically active compounds that are produced naturally through the polyketide pathway, which is critical for developing antibiotics and other therapeutics. He has led several research projects aimed at deciphering the complex biochemical processes involved in polyketide synthesis, including the function of multi-component enzyme systems like polyketide synthases.
University of Bristol • Bristol
Teaching and researching topics in biochemistry, specifically focusing on enzymology and polyketide biosynthesis.
Department of Physics research themes include Astrophysics, Materials and Devices, Particle Physics, and Quantum and Soft Matter.