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John William Hanna is an Associate Professor in the Department of Pathology, affiliated with the PhD Program in Biological Biomedical Sciences at Harvard University. His research focuses on the ubiquitin-proteasome system (UPS) and its role in the degradation of misfolded proteins, which are critical for cellular survival. Misfolded proteins have been linked to various neurodegenerative diseases, and his lab aims to elucidate the basic mechanisms of the UPS, applying these discoveries for clinical benefits. Hanna currently studies how cells sense and respond to misfolded proteins and explores the molecular mechanisms of proteasome function, emphasizing the interplay between protein degradation and lipid metabolism.
Brigham Women's Hospital • Boston, MA
Conducts research and teaches in the Department of Pathology, focusing on protein degradation and cellular mechanisms.
Administered by the Harvard Kenneth C. Griffin Graduate School of Arts and Sciences (GSAS).